| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC111564362 | LOC111564721 | ENSAOCP00000001469 | ENSAOCP00000027871 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.943 |
| LOC111564362 | LOC111570352 | ENSAOCP00000001469 | ENSAOCP00000028768 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Betaine-homocysteine methyltransferase. | 0.943 |
| LOC111564362 | LOC111581621 | ENSAOCP00000001469 | ENSAOCP00000015603 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.943 |
| LOC111564362 | LOC111582635 | ENSAOCP00000001469 | ENSAOCP00000031997 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Zgc:172121; Involved in the regulation of homocysteine metabolism. | 0.951 |
| LOC111564362 | LOC111585375 | ENSAOCP00000001469 | ENSAOCP00000015311 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Amine oxidase. | 0.907 |
| LOC111564362 | amd1 | ENSAOCP00000001469 | ENSAOCP00000020838 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-adenosylmethionine decarboxylase proenzyme. | 0.942 |
| LOC111564362 | gnmt | ENSAOCP00000001469 | ENSAOCP00000003074 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Glycine N-methyltransferase. | 0.934 |
| LOC111564362 | mat2b | ENSAOCP00000001469 | ENSAOCP00000015699 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.936 |
| LOC111564362 | mtr | ENSAOCP00000001469 | ENSAOCP00000028492 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.948 |
| LOC111564362 | tat | ENSAOCP00000001469 | ENSAOCP00000002242 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.941 |
| LOC111564721 | LOC111564362 | ENSAOCP00000027871 | ENSAOCP00000001469 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.943 |
| LOC111564721 | LOC111570352 | ENSAOCP00000027871 | ENSAOCP00000028768 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Betaine-homocysteine methyltransferase. | 0.901 |
| LOC111564721 | LOC111581621 | ENSAOCP00000027871 | ENSAOCP00000015603 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | 0.901 |
| LOC111564721 | LOC111582635 | ENSAOCP00000027871 | ENSAOCP00000031997 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Zgc:172121; Involved in the regulation of homocysteine metabolism. | 0.902 |
| LOC111564721 | LOC111585375 | ENSAOCP00000027871 | ENSAOCP00000015311 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Amine oxidase. | 0.901 |
| LOC111564721 | gnmt | ENSAOCP00000027871 | ENSAOCP00000003074 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Glycine N-methyltransferase. | 0.476 |
| LOC111564721 | mat2b | ENSAOCP00000027871 | ENSAOCP00000015699 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.941 |
| LOC111564721 | mtr | ENSAOCP00000027871 | ENSAOCP00000028492 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.937 |
| LOC111564721 | tat | ENSAOCP00000027871 | ENSAOCP00000002242 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.934 |
| LOC111570352 | LOC111564362 | ENSAOCP00000028768 | ENSAOCP00000001469 | Betaine-homocysteine methyltransferase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.943 |