Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
exo1Exonuclease 1. (782 aa)    
Predicted Functional Partners:
mlh1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
   
 0.996
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.996
msh2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.996
dna2
DNA replication helicase/nuclease 2.
   
 0.995
blm
BLM RecQ like helicase.
  
 0.993
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.991
rad50
RAD50 homolog, double strand break repair protein.
  
 0.990
recql4
RecQ helicase-like 4.
  
 0.986
rbbp8
CtIP_N domain-containing protein.
    
 0.984
pms2
PMS1 homolog 2, mismatch repair system component.
   
 0.983
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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