Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
dact1Dishevelled-binding antagonist of beta-catenin 1. (791 aa)    
Predicted Functional Partners:
LOC111571691
Dishevelled segment polarity protein 2.
    
 0.920
LOC111573553
Uncharacterized protein.
    
 0.872
ENSAOCP00000003773
DIX domain-containing protein.
    
 0.872
sestd1
SEC14 and spectrin domains 1.
    
 
 0.872
dvl1
Dishevelled segment polarity protein 1a.
    
 0.872
LOC111576801
Dishevelled segment polarity protein 3a.
    
 0.872
kiaa0586
Uncharacterized protein.
      
 0.766
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.755
VANGL1
Vang-like protein.
    
 
 0.754
psmf1
Proteasome inhibitor subunit 1.
      
 0.705
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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