STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf8Interferon regulatory factor 8. (422 aa)    
Predicted Functional Partners:
spi1
Spi-1 proto-oncogene b.
   
 
 0.902
il10
Interleukin 10.
   
 
 0.691
irf1
Interferon regulatory factor.
   
 0.656
LOC111570193
ETS domain-containing protein.
   
 
 0.641
LOC111586815
Signal transducer and activator of transcription.
    
 0.560
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.557
LOC111587249
Protein phosphatase 2, regulatory subunit A, beta b.
    
  0.536
esco2
Establishment of sister chromatid cohesion N-acetyltransferase 2.
      
 0.534
batf
Basic leucine zipper transcription factor, ATF-like.
   
 
 0.526
LOC111573454
Uncharacterized protein.
   
 0.522
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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