STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf8Interferon regulatory factor 8. (422 aa)    
Predicted Functional Partners:
spi1
Spi-1 proto-oncogene b.
   
 
 0.749
irf1
Interferon regulatory factor.
   
0.572
EGR2
Early growth response 2.
    
 0.491
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.488
mpeg1
Macrophage expressed 1, tandem duplicate 2.
   
  
 0.483
angptl7
Angiopoietin-like 7.
   
 0.473
LOC111573454
Uncharacterized protein.
   
 0.471
csf3r
Colony stimulating factor 3 receptor (granulocyte).
   
 0.471
Lcp1
Uncharacterized protein.
   
  
 0.470
CDC25B
Cell division cycle 25B.
   
 0.468
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.