Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tial1TIA1 cytotoxic granule-associated RNA binding protein-like 1. (394 aa)    
Predicted Functional Partners:
dcp1a
Decapping mRNA 1A.
   
 
 0.705
snrpc
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
   
 0.652
LOC111571676
RRM domain-containing protein.
  
 0.634
LOC111575058
RRM domain-containing protein.
  
 0.633
pabpn1
Poly(A) binding protein, nuclear 1.
  
 0.615
snrpd2
Small nuclear ribonucleoprotein Sm D2.
   
 0.613
atxn2
Ataxin 2.
   
 
 0.612
PABPN1L
Poly(A) binding protein nuclear 1 like, cytoplasmic.
  
 0.601
snrpe
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.599
cstf3
Cleavage stimulation factor, 3' pre-RNA, subunit 3.
   
 0.598
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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