Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fam20aFAM20A golgi associated secretory pathway pseudokinase. (533 aa)    
Predicted Functional Partners:
LOC111578213
FAM20C golgi associated secretory pathway kinase a.
    
 0.934
LOC111588427
Fam20C domain-containing protein.
    
 0.934
PRAG1
PEAK1 related, kinase-activating pseudokinase 1.
      
 0.811
tmem64
Transmembrane protein 64.
      
 0.790
LOC111588210
Fam20C domain-containing protein.
    
 0.783
LOC111584045
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
     
 0.732
LOC111585402
Alpha-2-HS-glycoprotein 2.
     
 0.728
LOC111566593
Uncharacterized protein.
      
 0.697
peak1
Pseudopodium-enriched atypical kinase 1.
      
 0.697
pan3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
      
 0.687
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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