Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arl2ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)    
Predicted Functional Partners:
arl2bp
ADP-ribosylation factor-like 2 binding protein.
   
 0.997
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
   
 0.994
tbcd
Tubulin folding cofactor D.
    
 0.984
tbcb
Tubulin folding cofactor B.
   
 
 0.949
unc119
Unc-119 lipid binding chaperone.
    
 
 0.948
LOC111580864
GMP_PDE_delta domain-containing protein.
    
 
 0.948
tbce
Tubulin folding cofactor E.
    
 
 0.942
Tbcc
Tubulin folding cofactor C.
    
 
 0.927
rp2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
    
 
 0.829
LOC111567724
Unc-119 lipid binding chaperone B homolog 2.
    
 
 0.706
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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