Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC111575485Kruppel-like factor 2b. (386 aa)    
Predicted Functional Partners:
LOC111564069
Uncharacterized protein.
  
  
 
0.901
LOC111582028
POU domain protein.
    
 0.617
LOC111577187
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.437
mysm1
Myb-like, SWIRM and MPN domains 1.
    
  0.436
LOC111588582
NME/NM23 family member 8; Belongs to the NDK family.
    
 0.434
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.430
LOC111579640
SRY-box transcription factor 3.
   
 0.423
Sox2
SRY-box transcription factor 2.
   
 0.423
lmo2
LIM domain only 2 (rhombotin-like 1).
   
 
 0.422
Cebpd
CCAAT enhancer binding protein delta.
   
 0.420
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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