Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1382 aa)    
Predicted Functional Partners:
mlh1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
 
 0.999
msh2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.999
pms2
PMS1 homolog 2, mismatch repair system component.
  
 0.998
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.997
pms1
PMS1 homolog 1, mismatch repair system component.
 
 0.997
exo1
Exonuclease 1.
   
 0.976
pold1
DNA polymerase.
   
 
 0.970
mlh3
WW domain-containing protein.
  
 0.963
pola1
DNA polymerase.
   
 
 0.956
blm
BLM RecQ like helicase.
  
 0.951
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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