Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kdrKinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1352 aa)    
Predicted Functional Partners:
vegfb
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.985
LOC111583272
Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.
    
 0.980
LOC111582761
Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.
    
 0.978
shc2
SHC (Src homology 2 domain containing) transforming protein 2.
   
 0.975
LOC111566758
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.969
LOC111582380
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.969
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 0.969
LOC111569137
Uncharacterized protein.
    
 0.969
LOC111582127
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.963
plcg1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.963
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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