Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nedd4NEDD4 E3 ubiquitin protein ligase a. (1014 aa)    
Predicted Functional Partners:
dlg3
Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family.
    
 0.919
nedd4l
NEDD4 like E3 ubiquitin protein ligase.
  
  
 
0.901
ndfip2
Nedd4 family interacting protein 2.
    
 
 0.891
rps27a
Ribosomal protein S27a.
    
  0.887
LOC111575124
Angiomotin.
    
 0.885
ENSAOCP00000017694
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.874
egfr
Receptor protein-tyrosine kinase.
    
 0.829
LOC111586710
Uncharacterized protein.
    
 0.829
LOC111585205
Uncharacterized protein; Belongs to the synuclein family.
    
 
 0.820
LOC111571920
Tyrosine-protein kinase receptor.
   
 0.805
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.