STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nedd4NEDD4 E3 ubiquitin protein ligase a. (1014 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
 0.879
arrdc3
Arrestin domain containing 3a.
    
 
 0.838
ENSAOCP00000017694
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.804
smad3
Mothers against decapentaplegic homolog.
    
 0.711
LOC111573031
Mothers against decapentaplegic homolog.
    
 0.711
LOC111583068
Mothers against decapentaplegic homolog.
    
 0.711
LOC111571476
Mothers against decapentaplegic homolog.
    
 0.711
smad6
Mothers against decapentaplegic homolog.
    
 0.701
smad7
Mothers against decapentaplegic homolog.
    
 0.701
LOC111565279
Mothers against decapentaplegic homolog.
    
 0.701
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.