Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hook1Hook microtubule-tethering protein 1. (716 aa)    
Predicted Functional Partners:
aktip
Akt interacting protein.
   
 
 0.929
dctn1
Dynactin 1a.
    
 
 0.836
fam160a1
Family with sequence similarity 160 member A1a.
    
 
 0.765
LOC111583556
Uncharacterized protein.
    
 
 0.765
LOC111574474
Family with sequence similarity 160 member A2.
    
 
 0.765
mcm4
DNA helicase; Belongs to the MCM family.
   
 
 0.693
BICD2
BICD cargo adaptor 2.
   
 
 0.683
LOC111571958
Bicaudal D homolog 2 (Drosophila).
   
 
 0.683
LOC111562643
Uncharacterized protein.
   
 
 0.652
hook2
Hook microtubule-tethering protein 2.
    
   0.649
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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