Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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LOC111567189Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (667 aa)    
Predicted Functional Partners:
LOC111583963
Luteinizing hormone, beta polypeptide.
   
 0.970
cga
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
   
 
 0.906
LOC111576087
Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
  
  
 
0.902
LOC111571034
Cys_knot domain-containing protein.
   
 0.865
LOC111585083
GNAS complex locus.
    
 0.766
LOC111579901
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
    
  0.754
LOC111583347
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.754
GNB4
G protein subunit beta 4.
    
  0.754
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
    
  0.754
LOC111578604
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.741
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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