STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111567189Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (667 aa)    
Predicted Functional Partners:
LOC111583963
Luteinizing hormone, beta polypeptide.
   
 0.828
LOC111571034
Cys_knot domain-containing protein.
   
 0.766
LOC111565746
Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family.
   
  
 0.701
dvl1
Dishevelled segment polarity protein 1a.
      
 0.692
sin3b
SIN3 transcription regulator family member B.
      
 0.692
crh
Corticotropin releasing hormone b.
      
 0.659
LOC111569336
CRF domain-containing protein.
      
 0.659
ENSAOCP00000017740
Cys_knot domain-containing protein.
    
 0.612
LOC111568011
Thyroid stimulating hormone subunit beta a.
    
 0.612
Cnot1
CCR4-NOT transcription complex, subunit 1.
      
 0.585
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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