Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC111579002Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)    
Predicted Functional Partners:
prkar1a
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b.
 
 
 0.982
pln
Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
    
 0.980
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.975
LOC111562596
Protein kinase, cAMP-dependent, regulatory, type I, beta.
   
 0.971
LOC111574377
Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.
   
 0.971
LOC111570013
Protein kinase, cAMP-dependent, regulatory, type II, alpha A.
   
 0.971
gli3
GLI family zinc finger 3.
    
 0.961
LOC111580119
Uncharacterized protein.
    
 0.960
gli1
GLI family zinc finger 1.
    
 0.960
gli2
GLI family zinc finger 2a.
    
 0.960
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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