| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSAOCP00000002667 | ENSAOCP00000025168 | ENSAOCP00000002667 | ENSAOCP00000025168 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | NFS1 cysteine desulfurase. | 0.996 |
| ENSAOCP00000002667 | MOCOS | ENSAOCP00000002667 | ENSAOCP00000002138 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.981 |
| ENSAOCP00000002667 | mocs3 | ENSAOCP00000002667 | ENSAOCP00000020189 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.436 |
| ENSAOCP00000002667 | scly | ENSAOCP00000002667 | ENSAOCP00000001284 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Selenocysteine lyase. | 0.979 |
| ENSAOCP00000025168 | ENSAOCP00000002667 | ENSAOCP00000025168 | ENSAOCP00000002667 | NFS1 cysteine desulfurase. | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.996 |
| ENSAOCP00000025168 | LOC111569365 | ENSAOCP00000025168 | ENSAOCP00000008240 | NFS1 cysteine desulfurase. | Cystathionase (cystathionine gamma-lyase), like. | 0.499 |
| ENSAOCP00000025168 | MOCOS | ENSAOCP00000025168 | ENSAOCP00000002138 | NFS1 cysteine desulfurase. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.811 |
| ENSAOCP00000025168 | iscu | ENSAOCP00000025168 | ENSAOCP00000010699 | NFS1 cysteine desulfurase. | Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.997 |
| ENSAOCP00000025168 | mocs3 | ENSAOCP00000025168 | ENSAOCP00000020189 | NFS1 cysteine desulfurase. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.998 |
| ENSAOCP00000025168 | suox | ENSAOCP00000025168 | ENSAOCP00000020499 | NFS1 cysteine desulfurase. | Sulfite oxidase. | 0.705 |
| LOC111567071 | MOCOS | ENSAOCP00000023578 | ENSAOCP00000002138 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.939 |
| LOC111567071 | gphn | ENSAOCP00000023578 | ENSAOCP00000029347 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Gephyrin b. | 0.900 |
| LOC111567071 | mocs3 | ENSAOCP00000023578 | ENSAOCP00000020189 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.563 |
| LOC111567071 | suox | ENSAOCP00000023578 | ENSAOCP00000020499 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Sulfite oxidase. | 0.797 |
| LOC111569365 | ENSAOCP00000025168 | ENSAOCP00000008240 | ENSAOCP00000025168 | Cystathionase (cystathionine gamma-lyase), like. | NFS1 cysteine desulfurase. | 0.499 |
| LOC111569365 | MOCOS | ENSAOCP00000008240 | ENSAOCP00000002138 | Cystathionase (cystathionine gamma-lyase), like. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.805 |
| LOC111569365 | scly | ENSAOCP00000008240 | ENSAOCP00000001284 | Cystathionase (cystathionine gamma-lyase), like. | Selenocysteine lyase. | 0.548 |
| LOC111569365 | suox | ENSAOCP00000008240 | ENSAOCP00000020499 | Cystathionase (cystathionine gamma-lyase), like. | Sulfite oxidase. | 0.974 |
| MOCOS | ENSAOCP00000002667 | ENSAOCP00000002138 | ENSAOCP00000002667 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.981 |
| MOCOS | ENSAOCP00000025168 | ENSAOCP00000002138 | ENSAOCP00000025168 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | NFS1 cysteine desulfurase. | 0.811 |