STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAOCP00000002199Uncharacterized protein; Belongs to the cytochrome P450 family. (150 aa)    
Predicted Functional Partners:
aasdh
Aminoadipate-semialdehyde dehydrogenase.
  
 0.582
LOC111565746
Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family.
  
 0.577
CYP19A1
Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 0.576
ENSAOCP00000019251
Si:dkey-91i10.3.
  
 
 0.565
ENSAOCP00000029301
Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
  
 
 0.544
LOC111575932
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 
 0.542
LOC111587899
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
 
 0.532
ndufab1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.530
bard1
BRCA1 associated RING domain 1.
    
 0.485
nbn
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.476
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.