STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111577096Zgc:171592; Belongs to the peptidase S1 family. (267 aa)    
Predicted Functional Partners:
LOC111574952
Macrophage stimulating 1 receptor a.
    
 0.598
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.598
mst1r
Macrophage stimulating 1 receptor b.
    
 0.598
mmp9
Matrix metallopeptidase 9.
   
 0.597
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
  
0.544
ENSAOCP00000023234
Peptidase S1 domain-containing protein.
  
 
0.508
LOC111577049
Peptidase S1 domain-containing protein.
  
 
0.496
LOC111564203
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
 
0.493
ENSAOCP00000023250
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
 
0.486
APP
Amyloid beta precursor protein.
    
 0.480
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.