Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ing4Inhibitor of growth protein. (248 aa)    
Predicted Functional Partners:
meaf6
MYST/Esa1-associated factor 6.
   
 0.972
jade2
Jade family PHD finger 2.
    
 0.919
LOC111577187
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.916
LOC111585429
Bromodomain and PHD finger containing, 3a.
    
 0.897
brpf3
Bromodomain and PHD finger containing, 3b.
    
 0.897
brpf1
Uncharacterized protein.
    
 0.896
jade1
Jade family PHD finger 1.
    
 0.885
jade3
Jade family PHD finger 3.
    
 0.838
LOC111567076
Bromodomain containing 1b.
    
 0.831
brd1
Bromodomain containing 1a.
    
 0.831
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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