Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nf2Neurofibromin 2b (merlin). (589 aa)    
Predicted Functional Partners:
LOC111575124
Angiomotin.
    
 0.992
amotl2
Angiomotin like 2a.
    
 0.983
LOC111578813
Angiomotin like 2b.
    
 0.983
lats1
Large tumor suppressor kinase 1.
    
 
 0.918
hgs
Hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 
 0.902
lats2
Large tumor suppressor kinase 2.
    
 
 0.869
LOC111563162
LisH domain-containing protein.
    
 
 0.838
DCAF1
DDB1 and CUL4 associated factor 1.
    
 
 0.838
sav1
Salvador family WW domain containing protein 1.
    
 
 0.801
ddb1
Damage-specific DNA binding protein 1.
    
   0.790
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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