Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC111584558Amyloid beta precursor protein binding family A member 3. (722 aa)    
Predicted Functional Partners:
hif1an
Hypoxia inducible factor 1 subunit alpha inhibitor.
    
 
 0.938
CASK
Uncharacterized protein; Belongs to the MAGUK family.
   
 0.898
LOC111575429
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 0.898
APP
Amyloid beta precursor protein.
   
 
 0.855
LOC111568091
Amyloid beta (A4) precursor protein b.
   
 
 0.855
mpp1
Membrane protein, palmitoylated 1; Belongs to the MAGUK family.
   
 0.807
LOC111580051
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.745
lin7b
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.745
dnajc17
DnaJ (Hsp40) homolog, subfamily C, member 17.
      
 0.727
Ibtk
ANK_REP_REGION domain-containing protein.
      
 0.705
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (24%) [HD]