Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
plgrktPlasminogen receptor, C-terminal lysine transmembrane protein. (149 aa)    
Predicted Functional Partners:
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
    
 
 0.652
suox
Sulfite oxidase.
      
 0.618
tgfbrap1
Transforming growth factor, beta receptor associated protein 1.
      
 0.600
ascc1
Activating signal cointegrator 1 complex subunit 1.
      
 0.548
hpn
Hepsin; Belongs to the peptidase S1 family.
    
 
 0.517
tcea3
Transcription elongation factor A (SII), 3.
   
  
 0.516
gng10
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.502
mien1
Selenoprotein W, 2b.
      
 0.488
LOC111571035
ADP-ribosylation factor-like 14 effector protein.
   
  
 0.484
ENSAOCP00000016692
ARF7EP_C domain-containing protein.
   
  
 0.484
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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