Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSAOCP00000003689Uncharacterized protein. (312 aa)    
Predicted Functional Partners:
ercc1
Excision repair cross-complementation group 1.
   
 0.931
xpa
Xeroderma pigmentosum, complementation group A.
    
 0.900
slx4
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).
   
 0.888
ercc3
Excision repair cross-complementation group 3.
  
 0.856
mus81
MUS81 structure-specific endonuclease subunit.
    
 0.841
ercc2
Excision repair cross-complementation group 2.
   
 0.837
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.807
fancg
FA complementation group G.
    
 0.803
faap24
FA core complex associated protein 24.
   
 0.794
fancl
FA complementation group L.
    
 0.792
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.