STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAOCP00000003689Uncharacterized protein. (312 aa)    
Predicted Functional Partners:
ercc1
Excision repair cross-complementation group 1.
   
 0.888
xpa
Xeroderma pigmentosum, complementation group A.
    
 0.835
fancl
FA complementation group L.
    
 0.803
slx4
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).
   
 0.798
fancb
FA complementation group B.
   
 0.797
fancg
FA complementation group G.
    
 0.796
faap24
FA core complex associated protein 24.
   
 0.793
fancc
FA complementation group C.
   
 0.775
mus81
MUS81 structure-specific endonuclease subunit.
    
 0.775
top3a
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.765
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.