Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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[Homology]
Score
cln3Battenin. (435 aa)    
Predicted Functional Partners:
ppt1
Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).
    
 
 0.924
cln5
CLN5 intracellular trafficking protein.
    
 
 0.919
cln6
CLN6 transmembrane ER protein a.
   
  
 0.908
cln8
CLN8 transmembrane ER and ERGIC protein.
      
 0.878
tpp1
Tripeptidyl peptidase I.
      
 0.874
mfsd8
Major facilitator superfamily domain containing 8.
    
 
 0.809
LOC111579232
Cytochrome c oxidase assembly homolog 15 (yeast).
    
   0.770
rpn2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
    
   0.770
aup1
AUP1 lipid droplet regulating VLDL assembly factor.
    
   0.770
slc25a11
Solute carrier family 25 member 11; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
   0.770
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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