Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
afdnAfadin, adherens junction formation factor a. (1887 aa)    
Predicted Functional Partners:
nectin1
Nectin cell adhesion molecule 1b.
    
 0.965
nectin3
Uncharacterized protein.
    
 0.956
LOC111579865
Nectin cell adhesion molecule 3b.
    
 0.956
LOC111576573
Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family.
   
 
 0.861
LOC111567642
Uncharacterized protein.
    
 
 0.828
LOC111577702
Tight junction protein 1b; Belongs to the MAGUK family.
   
 
 0.822
LOC111572856
Tight junction protein 1a; Belongs to the MAGUK family.
   
 
 0.822
ENSAOCP00000012223
Tight junction protein 3; Belongs to the MAGUK family.
   
 
 0.802
vcl
Vinculin b.
   
 
 0.801
LOC111581406
Vinculin a.
   
 
 0.801
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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