Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC111571920Tyrosine-protein kinase receptor. (1418 aa)    
Predicted Functional Partners:
LOC111566540
Insulin receptor substrate 2a.
    
 0.977
LOC111575407
Insulin receptor substrate 4a.
    
 0.977
irs2
Insulin receptor substrate 2b.
    
 0.977
LOC111571694
Si:ch73-335l21.1.
    
 0.977
LOC111582532
Insulin-like growth factor 2b.
    
 0.975
LOC111573420
Growth factor receptor-bound protein 10b.
    
 0.967
LOC111562437
Growth factor receptor-bound protein 10a.
    
 0.967
grb2
Growth factor receptor-bound protein 2b.
   
 0.960
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.949
igf1
Insulin-like growth factor 1.
   
 
 0.943
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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