Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC111564203Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (245 aa)    
Predicted Functional Partners:
LOC111586722
Zgc:136461; Belongs to the peptidase S1 family.
  
 
0.607
LOC111586187
Alpha-1-microglobulin/bikunin precursor.
   
 0.595
LOC111567950
Zgc:112160; Belongs to the peptidase S1 family.
   
  0.555
LOC111577096
Zgc:171592; Belongs to the peptidase S1 family.
   
  0.531
aplp2
Amyloid beta (A4) precursor-like protein 2.
    
  0.498
LOC111588582
NME/NM23 family member 8; Belongs to the NDK family.
    
 0.484
APP
Amyloid beta precursor protein.
    
 0.454
LOC111568091
Amyloid beta (A4) precursor protein b.
    
 0.454
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 
 0.420
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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