Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
spry4Sprouty homolog 4 (Drosophila). (293 aa)    
Predicted Functional Partners:
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
      
 0.920
Zbtb16
Zinc finger and BTB domain containing 16a.
      
 0.919
rnaseh2a
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
      
 0.914
htr5a
5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b.
      
 0.908
LOC111575915
Lysosomal protein transmembrane 4 beta.
    
   0.858
LOC111562643
Uncharacterized protein.
      
 0.805
bri3
Brain protein I3.
    
   0.765
LOC111564200
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.735
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.735
LOC111586006
Uncharacterized protein.
    
 0.735
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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