| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSAOCP00000010222 | LOC111576552 | ENSAOCP00000010222 | ENSAOCP00000005064 | Amino_oxidase domain-containing protein. | Lysine (K)-specific demethylase 4B. | 0.583 |
| ENSAOCP00000010222 | kdm1a | ENSAOCP00000010222 | ENSAOCP00000027418 | Amino_oxidase domain-containing protein. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.846 |
| ENSAOCP00000010222 | rps27a | ENSAOCP00000010222 | ENSAOCP00000002842 | Amino_oxidase domain-containing protein. | Ribosomal protein S27a. | 0.541 |
| LOC111568069 | LOC111576552 | ENSAOCP00000027868 | ENSAOCP00000005064 | Uncharacterized protein. | Lysine (K)-specific demethylase 4B. | 0.525 |
| LOC111568069 | ar | ENSAOCP00000027868 | ENSAOCP00000012605 | Uncharacterized protein. | Androgen receptor. | 0.902 |
| LOC111568069 | kdm1a | ENSAOCP00000027868 | ENSAOCP00000027418 | Uncharacterized protein. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.934 |
| LOC111568069 | pias4 | ENSAOCP00000027868 | ENSAOCP00000023704 | Uncharacterized protein. | Protein inhibitor of activated STAT, 4a. | 0.695 |
| LOC111576552 | ENSAOCP00000010222 | ENSAOCP00000005064 | ENSAOCP00000010222 | Lysine (K)-specific demethylase 4B. | Amino_oxidase domain-containing protein. | 0.583 |
| LOC111576552 | LOC111568069 | ENSAOCP00000005064 | ENSAOCP00000027868 | Lysine (K)-specific demethylase 4B. | Uncharacterized protein. | 0.525 |
| LOC111576552 | LOC111583696 | ENSAOCP00000005064 | ENSAOCP00000004420 | Lysine (K)-specific demethylase 4B. | Tumor protein p53 binding protein, 1. | 0.568 |
| LOC111576552 | ar | ENSAOCP00000005064 | ENSAOCP00000012605 | Lysine (K)-specific demethylase 4B. | Androgen receptor. | 0.525 |
| LOC111576552 | atm | ENSAOCP00000005064 | ENSAOCP00000019655 | Lysine (K)-specific demethylase 4B. | Non-specific serine/threonine protein kinase. | 0.556 |
| LOC111576552 | kdm1a | ENSAOCP00000005064 | ENSAOCP00000027418 | Lysine (K)-specific demethylase 4B. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.779 |
| LOC111576552 | kdm3b | ENSAOCP00000005064 | ENSAOCP00000024951 | Lysine (K)-specific demethylase 4B. | Lysine (K)-specific demethylase 3B. | 0.539 |
| LOC111576552 | pias4 | ENSAOCP00000005064 | ENSAOCP00000023704 | Lysine (K)-specific demethylase 4B. | Protein inhibitor of activated STAT, 4a. | 0.532 |
| LOC111576552 | rnf168 | ENSAOCP00000005064 | ENSAOCP00000025786 | Lysine (K)-specific demethylase 4B. | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] | 0.554 |
| LOC111576552 | rps27a | ENSAOCP00000005064 | ENSAOCP00000002842 | Lysine (K)-specific demethylase 4B. | Ribosomal protein S27a. | 0.540 |
| LOC111583696 | LOC111576552 | ENSAOCP00000004420 | ENSAOCP00000005064 | Tumor protein p53 binding protein, 1. | Lysine (K)-specific demethylase 4B. | 0.568 |
| LOC111583696 | atm | ENSAOCP00000004420 | ENSAOCP00000019655 | Tumor protein p53 binding protein, 1. | Non-specific serine/threonine protein kinase. | 0.996 |
| LOC111583696 | kdm1a | ENSAOCP00000004420 | ENSAOCP00000027418 | Tumor protein p53 binding protein, 1. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.491 |
