Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbxl12F-box domain-containing protein. (408 aa)    
Predicted Functional Partners:
cul1
Cullin 1b; Belongs to the cullin family.
   
 0.985
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.969
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.913
fbxw8
F-box and WD repeat domain containing 8.
    
 0.740
srp72
Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.
      
 0.705
UBL5
Ubiquitin like 5.
      
 0.705
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.626
LOC111579028
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.626
styx
Serine/threonine/tyrosine interacting protein.
    
   0.592
pif1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
   
  
 0.546
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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