STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phox2bPaired like homeobox 2Bb. (285 aa)    
Predicted Functional Partners:
hand2
Heart and neural crest derivatives expressed 2.
   
 
 0.593
th
Tyrosine hydroxylase.
   
  
 0.518
LOC111586653
Tyrosine hydroxylase 2.
   
  
 0.518
LOC111588455
Uncharacterized protein.
      
 0.508
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
      
 0.459
LOC111585460
MYCN proto-oncogene, bHLH transcription factor.
      
 0.446
LHX3
LIM homeobox 3.
      
0.436
LOC111578879
LIM homeobox 4.
      
0.436
LOC111579575
Insulinoma-associated 1b.
   
  
 0.432
INSM2
INSM transcriptional repressor 2.
   
  
 0.432
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.