Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)    
Predicted Functional Partners:
LOC111581736
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.996
LOC111576372
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.987
tgfb2
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.987
LOC111568923
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.980
LOC111572013
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.980
smad3
Mothers against decapentaplegic homolog.
   
 0.967
LOC111573031
Mothers against decapentaplegic homolog.
   
 0.967
LOC111583068
Mothers against decapentaplegic homolog.
   
 0.967
LOC111571476
Mothers against decapentaplegic homolog.
   
 0.967
smurf1
E3 ubiquitin-protein ligase.
    
 0.966
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (16%) [HD]