Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC111580596Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (298 aa)    
Predicted Functional Partners:
ankrd22
Ankyrin repeat domain 22.
      
 0.510
LOC111579446
Proline rich Gla (G-carboxyglutamic acid) 2.
      
 0.460
psenen
Presenilin enhancer, gamma-secretase subunit.
      
 0.435
NCSTN
Nicastrin.
      
 0.430
magi3
Membrane associated guanylate kinase, WW and PDZ domain containing 3b.
   
 
 0.421
LOC111572763
Presenilin associated, rhomboid-like a.
      
 0.421
ENSAOCP00000021270
PDZ domain-containing protein.
   
 
 0.421
LOC111584927
Uncharacterized protein.
   
 
 0.421
parl
Rhomboid domain-containing protein.
      
 0.421
rhbdd1
Rhomboid domain containing 1.
      
 0.415
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.