Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kdsr3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (359 aa)    
Predicted Functional Partners:
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
     
 0.995
LOC111578261
Serine palmitoyltransferase, long chain base subunit 2b.
     
 0.980
LOC111562589
Serine palmitoyltransferase, long chain base subunit 2a.
     
 0.980
sptlc3
Serine palmitoyltransferase, long chain base subunit 3.
     
 0.980
LOC111574733
Sphingosine kinase 2.
     
 0.961
SPHK1
Sphingosine kinase 1.
     
 0.959
asah1
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
     
 0.959
cers5
Ceramide synthase 5.
     
 0.953
cers6
Ceramide synthase 6.
     
 0.953
CERS5
Ceramide synthase 5.
     
 0.953
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (18%) [HD]