Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aifm1Apoptosis inducing factor mitochondrion associated 1. (855 aa)    
Predicted Functional Partners:
LOC111565098
Coiled-coil-helix-coiled-coil-helix domain containing 4a.
    
 
 0.962
endog
Endonuclease.
    
 
 0.953
LOC111576238
Zgc:153993.
    
 0.927
ndufs5
NADH:ubiquinone oxidoreductase subunit S5.
    
 
 0.926
ak2
Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
   
 
 0.918
bax
BCL2 associated X, apoptosis regulator a.
    
 0.918
LOC111562459
Uncharacterized protein.
    
 0.912
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.899
LOC111571239
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.889
otud1
OTU deubiquitinase 1.
    
   0.861
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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