Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
aptxAprataxin. (333 aa)    
Predicted Functional Partners:
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1.
    
 
 0.988
hus1
Checkpoint protein; Belongs to the HUS1 family.
   
  
 0.950
tdp1
Tyrosyl-DNA phosphodiesterase 1.
    
 
 0.932
LOC111576022
Uncharacterized protein.
    
 
 0.927
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 
 0.918
APLF
Aprataxin and PNKP like factor.
      
 0.891
parp2
Poly [ADP-ribose] polymerase.
   
 
 0.872
lig3
DNA ligase.
    
 
 0.865
lig4
DNA ligase.
    
 
 0.759
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
      
 0.757
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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