Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC111567654Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (307 aa)    
Predicted Functional Partners:
LOC111571005
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.774
LOC111567878
Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.774
LOC111588521
Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.771
sigmar1
Sigma non-opioid intracellular receptor 1.
   
 
 0.521
fads2
Fatty acid desaturase 2.
     
 0.469
ENSAOCP00000009968
SEA domain-containing protein.
      
 0.432
ENSAOCP00000009984
Uncharacterized protein.
      
 0.432
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
   
 
 0.416
LOC111573670
Trans-2,3-enoyl-CoA reductase a.
    
 
 0.411
ENSAOCP00000009590
Trans-2,3-enoyl-CoA reductase-like 2a.
    
 
 0.411
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: low (8%) [HD]