Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
prpf39PRP39 pre-mRNA processing factor 39 homolog (yeast). (783 aa)    
Predicted Functional Partners:
snrpc
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
   
 0.903
Snrpf
Small nuclear ribonucleoprotein polypeptide F.
    
 0.881
snrnp70
Small nuclear ribonucleoprotein 70 (U1).
   
 0.878
sf3b1
Splicing factor 3b, subunit 1.
   
 
 0.858
trnau1ap
tRNA selenocysteine 1 associated protein 1a.
   
 
 0.838
LOC111583324
tRNA selenocysteine 1 associated protein 1b.
   
 
 0.838
luc7l
LUC7-like (S. cerevisiae).
   
 0.828
LOC111570166
Zgc:158803.
   
 0.828
pnisr
Uncharacterized protein.
   
  
 0.820
snrpa1
Small nuclear ribonucleoprotein polypeptide A.
    
 
 0.794
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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