| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HDAC3 | LOC111574649 | ENSAOCP00000004023 | ENSAOCP00000006783 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Nuclear receptor subfamily 2, group C, member 1. | 0.823 |
| HDAC3 | LOC111579416 | ENSAOCP00000004023 | ENSAOCP00000008331 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.468 |
| HDAC3 | kdm1a | ENSAOCP00000004023 | ENSAOCP00000027418 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.970 |
| HDAC3 | med1 | ENSAOCP00000004023 | ENSAOCP00000017723 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.581 |
| HDAC3 | ncor1 | ENSAOCP00000004023 | ENSAOCP00000010684 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Nuclear receptor corepressor 1. | 0.979 |
| HDAC3 | ncor2 | ENSAOCP00000004023 | ENSAOCP00000006616 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Nuclear receptor corepressor 2. | 0.973 |
| HDAC3 | nrip1 | ENSAOCP00000004023 | ENSAOCP00000001947 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Nuclear receptor interacting protein 1b. | 0.744 |
| HDAC3 | ube2i | ENSAOCP00000004023 | ENSAOCP00000025033 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. | 0.468 |
| LOC111570284 | LOC111574649 | ENSAOCP00000016072 | ENSAOCP00000006783 | JAZF zinc finger 1b. | Nuclear receptor subfamily 2, group C, member 1. | 0.585 |
| LOC111574649 | HDAC3 | ENSAOCP00000006783 | ENSAOCP00000004023 | Nuclear receptor subfamily 2, group C, member 1. | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.823 |
| LOC111574649 | LOC111570284 | ENSAOCP00000006783 | ENSAOCP00000016072 | Nuclear receptor subfamily 2, group C, member 1. | JAZF zinc finger 1b. | 0.585 |
| LOC111574649 | LOC111578371 | ENSAOCP00000006783 | ENSAOCP00000019926 | Nuclear receptor subfamily 2, group C, member 1. | Peptidylprolyl isomerase. | 0.692 |
| LOC111574649 | LOC111579416 | ENSAOCP00000006783 | ENSAOCP00000008331 | Nuclear receptor subfamily 2, group C, member 1. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.633 |
| LOC111574649 | kdm1a | ENSAOCP00000006783 | ENSAOCP00000027418 | Nuclear receptor subfamily 2, group C, member 1. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.589 |
| LOC111574649 | med1 | ENSAOCP00000006783 | ENSAOCP00000017723 | Nuclear receptor subfamily 2, group C, member 1. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.659 |
| LOC111574649 | ncor1 | ENSAOCP00000006783 | ENSAOCP00000010684 | Nuclear receptor subfamily 2, group C, member 1. | Nuclear receptor corepressor 1. | 0.636 |
| LOC111574649 | ncor2 | ENSAOCP00000006783 | ENSAOCP00000006616 | Nuclear receptor subfamily 2, group C, member 1. | Nuclear receptor corepressor 2. | 0.636 |
| LOC111574649 | nrip1 | ENSAOCP00000006783 | ENSAOCP00000001947 | Nuclear receptor subfamily 2, group C, member 1. | Nuclear receptor interacting protein 1b. | 0.840 |
| LOC111574649 | ube2i | ENSAOCP00000006783 | ENSAOCP00000025033 | Nuclear receptor subfamily 2, group C, member 1. | Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. | 0.633 |
| LOC111578371 | LOC111574649 | ENSAOCP00000019926 | ENSAOCP00000006783 | Peptidylprolyl isomerase. | Nuclear receptor subfamily 2, group C, member 1. | 0.692 |
