Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC111588194MSS51 mitochondrial translational activator. (384 aa)    
Predicted Functional Partners:
LOC111577750
Translational activator of mitochondrially encoded cytochrome c oxidase I.
      
 0.615
COX14
Cytochrome c oxidase assembly factor COX14.
      
 0.593
qrsl1
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily.
      
 0.544
pglyrp2
Peptidoglycan recognition protein 6.
      
 0.544
trmu
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase.
    
 
 0.526
LOC111575440
Lysine (K)-specific demethylase 6A, like.
   
 0.498
kdm6b
Lysine (K)-specific demethylase 6B, a.
   
 0.498
kdm6a
Lysine (K)-specific demethylase 6A.
   
 0.498
ENSAOCP00000020710
Lysine (K)-specific demethylase 6B, b.
   
 0.498
LOC111577187
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
  0.478
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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