STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rchy1Uncharacterized protein. (279 aa)    
Predicted Functional Partners:
polh
Polymerase (DNA directed), eta.
    
 0.963
LOC111577187
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.922
rps27a
Ribosomal protein S27a.
    
 0.759
poli
Polymerase (DNA directed) iota.
    
 0.717
rfc3
Replication factor C (activator 1) 3.
   
 
  0.657
rfc2
Replication factor C (activator 1) 2.
   
 
  0.648
rfc5
Replication factor C (activator 1) 5.
   
 
  0.648
rfc4
Replication factor C (activator 1) 4.
   
 
  0.648
ar
Androgen receptor.
    
 
 0.617
LOC111568069
Uncharacterized protein.
    
 
 0.617
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
Server load: medium (44%) [HD]