atic protein (Amphiprion ocellaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Amphiprion ocellaris

NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAOCP00000020521	LOC111562721	ENSAOCP00000020521	ENSAOCP00000016575	AIRC domain-containing protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.857
ENSAOCP00000020521	LOC111564887	ENSAOCP00000020521	ENSAOCP00000004602	AIRC domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.538
ENSAOCP00000020521	LOC111581159	ENSAOCP00000020521	ENSAOCP00000005554	AIRC domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.538
ENSAOCP00000020521	LOC111585580	ENSAOCP00000020521	ENSAOCP00000024936	AIRC domain-containing protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.857
ENSAOCP00000020521	LOC111587996	ENSAOCP00000020521	ENSAOCP00000027619	AIRC domain-containing protein.	ATP-grasp domain-containing protein.	0.999
ENSAOCP00000020521	adsl	ENSAOCP00000020521	ENSAOCP00000024950	AIRC domain-containing protein.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.999
ENSAOCP00000020521	adss1	ENSAOCP00000020521	ENSAOCP00000007973	AIRC domain-containing protein.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.933
ENSAOCP00000020521	atic	ENSAOCP00000020521	ENSAOCP00000007548	AIRC domain-containing protein.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.992
ENSAOCP00000020521	gart	ENSAOCP00000020521	ENSAOCP00000019438	AIRC domain-containing protein.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.999
ENSAOCP00000020521	ppat	ENSAOCP00000020521	ENSAOCP00000001665	AIRC domain-containing protein.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.998
LOC111562721	ENSAOCP00000020521	ENSAOCP00000016575	ENSAOCP00000020521	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	AIRC domain-containing protein.	0.857
LOC111562721	LOC111564887	ENSAOCP00000016575	ENSAOCP00000004602	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.952
LOC111562721	LOC111581159	ENSAOCP00000016575	ENSAOCP00000005554	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.952
LOC111562721	LOC111585580	ENSAOCP00000016575	ENSAOCP00000024936	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.902
LOC111562721	LOC111587996	ENSAOCP00000016575	ENSAOCP00000027619	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	ATP-grasp domain-containing protein.	0.961
LOC111562721	adsl	ENSAOCP00000016575	ENSAOCP00000024950	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.994
LOC111562721	adss1	ENSAOCP00000016575	ENSAOCP00000007973	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.901
LOC111562721	atic	ENSAOCP00000016575	ENSAOCP00000007548	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.988
LOC111562721	gart	ENSAOCP00000016575	ENSAOCP00000019438	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.961
LOC111562721	ppat	ENSAOCP00000016575	ENSAOCP00000001665	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.621