node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSAOCP00000023172 | LOC111577187 | ENSAOCP00000023172 | ENSAOCP00000001385 | RING-type domain-containing protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.977 |
ENSAOCP00000023172 | LOC111580447 | ENSAOCP00000023172 | ENSAOCP00000027561 | RING-type domain-containing protein. | Ubiquitin specific peptidase 7 (herpes virus-associated). | 0.892 |
ENSAOCP00000023172 | LOC111581531 | ENSAOCP00000023172 | ENSAOCP00000017959 | RING-type domain-containing protein. | Ubiquitin carboxyl-terminal hydrolase. | 0.892 |
ENSAOCP00000023172 | LOC111582895 | ENSAOCP00000023172 | ENSAOCP00000011739 | RING-type domain-containing protein. | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | 0.925 |
ENSAOCP00000023172 | atm | ENSAOCP00000023172 | ENSAOCP00000019655 | RING-type domain-containing protein. | Non-specific serine/threonine protein kinase. | 0.851 |
ENSAOCP00000023172 | daxx | ENSAOCP00000023172 | ENSAOCP00000003766 | RING-type domain-containing protein. | Death-domain associated protein. | 0.876 |
ENSAOCP00000023172 | mdm4 | ENSAOCP00000023172 | ENSAOCP00000009207 | RING-type domain-containing protein. | MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. | 0.975 |
ENSAOCP00000023172 | rb1 | ENSAOCP00000023172 | ENSAOCP00000006458 | RING-type domain-containing protein. | Retinoblastoma 1. | 0.836 |
ENSAOCP00000023172 | rpl11 | ENSAOCP00000023172 | ENSAOCP00000017066 | RING-type domain-containing protein. | Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. | 0.942 |
ENSAOCP00000023172 | rps27a | ENSAOCP00000023172 | ENSAOCP00000002842 | RING-type domain-containing protein. | Ribosomal protein S27a. | 0.939 |
LOC111577187 | ENSAOCP00000023172 | ENSAOCP00000001385 | ENSAOCP00000023172 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | RING-type domain-containing protein. | 0.977 |
LOC111577187 | LOC111580447 | ENSAOCP00000001385 | ENSAOCP00000027561 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Ubiquitin specific peptidase 7 (herpes virus-associated). | 0.963 |
LOC111577187 | LOC111581531 | ENSAOCP00000001385 | ENSAOCP00000017959 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Ubiquitin carboxyl-terminal hydrolase. | 0.963 |
LOC111577187 | LOC111582895 | ENSAOCP00000001385 | ENSAOCP00000011739 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | 0.861 |
LOC111577187 | atm | ENSAOCP00000001385 | ENSAOCP00000019655 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Non-specific serine/threonine protein kinase. | 0.998 |
LOC111577187 | daxx | ENSAOCP00000001385 | ENSAOCP00000003766 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Death-domain associated protein. | 0.946 |
LOC111577187 | mdm4 | ENSAOCP00000001385 | ENSAOCP00000009207 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. | 0.999 |
LOC111577187 | rb1 | ENSAOCP00000001385 | ENSAOCP00000006458 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Retinoblastoma 1. | 0.655 |
LOC111577187 | rpl11 | ENSAOCP00000001385 | ENSAOCP00000017066 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. | 0.875 |
LOC111577187 | rps27a | ENSAOCP00000001385 | ENSAOCP00000002842 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Ribosomal protein S27a. | 0.942 |