STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111571549Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (551 aa)    
Predicted Functional Partners:
mgll
Monoglyceride lipase.
     
 0.910
mogat2
Monoacylglycerol O-acyltransferase 2.
   
 
 0.901
dhcr24
24-dehydrocholesterol reductase.
     
 0.900
dhcr7
7-dehydrocholesterol reductase.
     
  0.900
PNLIPRP2
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 0.821
LOC111578258
Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4; Belongs to the cytochrome P450 family.
     
 0.808
LOC111576985
Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
     
 0.803
LOC111587899
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
   
  0.802
sts
Steroid sulfatase (microsomal), isozyme S.
     
 0.801
dgke
Diacylglycerol kinase.
     
 0.680
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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