Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ovol1Ovo-like zinc finger 1a. (340 aa)    
Predicted Functional Partners:
sdhaf1
Succinate dehydrogenase assembly factor 1, mitochondrial.
      
 0.677
nsun2
NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.618
ubr3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
    
 
 0.503
mrpl24
Mitochondrial ribosomal protein L24.
      
 0.487
snx6
Sorting nexin; Involved in several stages of intracellular trafficking.
      
 0.480
snx5
Sorting nexin; Involved in several stages of intracellular trafficking.
      
 0.480
asz1
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
      
 0.478
spo11
SPO11 initiator of meiotic double stranded breaks.
      
 0.477
PRADC1
Protease associated domain containing 1.
      
 0.454
Prodh2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.444
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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