Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ttkTtk protein kinase. (997 aa)    
Predicted Functional Partners:
mad1l1
Mitotic arrest deficient 1 like 1.
    
 0.997
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.997
Ndc80
NDC80 kinetochore complex component.
   
 
 0.996
nuf2
UF2 component of NDC80 kinetochore complex.
   
 
 0.995
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 
 0.993
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 
 0.992
cdca8
Cell division cycle associated 8.
   
 
 0.988
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.982
cenpe
Centromere-associated protein E isoform X1.
   
 
 0.975
ncapg
Non-SMC condensin I complex, subunit G.
   
  
 0.964
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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