Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
I3ITY3_ORENIXPG_I_2 domain-containing protein. (682 aa)    
Predicted Functional Partners:
fancm
Uncharacterized protein.
    
 0.553
mus81
MUS81 structure-specific endonuclease subunit.
    
 0.501
taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B.
      
 0.486
pold2
Polymerase (DNA directed), delta 2, regulatory subunit.
    
 0.462
ddx20
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.
   
 0.453
ubxn7
UBX domain protein 7.
     
 0.450
tubgcp2
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.449
tmem108
Transmembrane protein 108.
      
 0.443
Pold1
DNA polymerase.
    
 0.434
cmpk2
Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial.
   
  
 0.419
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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