Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arhgef37Rho guanine nucleotide exchange factor (GEF) 37. (768 aa)    
Predicted Functional Partners:
Bin3
Bridging integrator 3.
    
 
 0.791
I3KSR5_ORENI
MCF.2 cell line derived transforming sequence-like 2.
     
 0.745
ENSONIP00000000682
Intersectin 2a.
    
 0.654
I3KKD0_ORENI
Intersectin 2b.
    
 0.654
itsn1
Intersectin 1 (SH3 domain protein).
    
 0.651
arhgef12
Rho guanine nucleotide exchange factor (GEF) 12a.
   
 
 0.651
mrps22
Mitochondrial ribosomal protein S22.
      
 0.646
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
    
 0.633
arhgef39
Rho guanine nucleotide exchange factor (GEF) 39.
    
 0.558
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17.
     
 0.545
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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