Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
ube3dUbiquitin protein ligase E3D. (400 aa)    
Predicted Functional Partners:
CPSF3
Cleavage and polyadenylation specific factor 3.
    
 
 0.914
LOC100692710
Cleavage and polyadenylation specific factor 3.
    
 
 0.914
LOC100703750
Uncharacterized protein.
    
 0.902
ENSONIP00000062029
annotation not available
    
 0.902
Ube2c
Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.882
memo1
Mediator of cell motility 1.
    
   0.876
LOC100691569
Cytochrome b5 reductase 4.
      
 0.696
pudp
Pseudouridine 5'-phosphatase.
      
 0.624
LOC100703333
ADNP homeobox 2b.
      
 0.620
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
    
 
 0.588
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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