Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Dop1aDOP1 leucine zipper like protein A. (2486 aa)    
Predicted Functional Partners:
Mon2
MON2 homolog, regulator of endosome-to-Golgi trafficking.
   
 
 0.878
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
    
   0.762
trap1
TNF receptor-associated protein 1.
    
   0.758
cryzl1
Crystallin, zeta (quinone reductase)-like 1.
      
 0.686
slc66a2
Solute carrier family 66 member 2.
    
 
 0.680
LOC100711201
Si:dkey-246g23.2.
    
 
 0.680
pus7
Pseudouridine synthase 7.
      
 0.577
lratd1
LRAT domain containing 1.
      
 0.485
kiaa0355
Si:ch211-79l17.1.
      
 0.484
mrpl39
Mitochondrial ribosomal protein L39.
      
 0.480
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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