STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3IW43_ORENIG_PROTEIN_RECEP_F1_2 domain-containing protein. (316 aa)    
Predicted Functional Partners:
NPFFR2
Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.517
LOC100699672
Neuropeptide FF receptor 2b; Belongs to the G-protein coupled receptor 1 family.
      
 0.517
HRH1
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
     
 0.506
Gria2
Glutamate receptor, ionotropic, AMPA 2b.
    
 0.503
LOC100706002
Glutamate receptor, ionotropic, AMPA 4a.
    
 0.503
LOC100700102
Glutamate receptor, metabotropic 5a.
     
 0.493
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
      
 0.489
LOC100691234
Cholinergic receptor, nicotinic, alpha 1 (muscle).
      
 0.489
syk
Tyrosine-protein kinase.
     
 0.487
I3IUC5_ORENI
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.485
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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